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Making inferences from random samples

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Getaway Travel Agency surveyed a random sample of 45 of their clients about their vacation plans. Of the clients surveyed, 21 expected that they would go on 3 vacations in the next year. There are 516 Getaway Travel Agency clients.
Based on the data, what is the most reasonable estimate for the number of Getaway Travel Agency clients who expect to go on 3 vacations in the next year?
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